Benefits: We show for the first time which the differentiation of hmoDCs in the existence of WIN55,212-2 generates tolerogenic Earn-hmoDCs which have been considerably less responsive to LPS stimulation and in the position to prime Tregs. WIN55,212-two also impairs the pro-inflammatory polarization of human macrophages by inhibiting cytokine creation, inflammasome https://win55.clinic/the-thao