Poor/Substantial Metabolizers, CYP2D6 The formation of the Energetic metabolite, M1, is mediated by CYP2D6, a polymorphic enzyme. Close to 7% in the populace has decreased action in the CYP2D6 isoenzyme of cytochrome P450 metabolizing enzyme system. These people are “very poor metabolizers” of debrisoquine, dextromethorphan and tricyclic antidepressants, between other https://davidv208din2.blogspothub.com/profile