Indeed, TERT phosphorylation has been demonstrated for being needed for telomerase activation. b Influence of BETi on telomere regulation. BETi compete with acetylated histones for that binding on the BRD4 bromodomains releasing BRD4 from shorter telomere, destabilizing telomere safety complex Business and minimizing Telomerase activity. The progressive shortening of telomere https://connernanyi.nizarblog.com/32031726/helping-the-others-realize-the-advantages-of-jq-1-in-epigenetics