Substitution at R3 which has a halogen or alkoxy group (74f–74i) triggered a slight rise in cellular potency Using the halide analogs (74g–h) showing best the potency during the group. Even further optimization brought about the discovery of 74i–j, with 74k as the most Lively compound during the sequence (pIC50 https://paxtonsndrf.activosblog.com/30686424/little-known-facts-about-buy-indazole