Substitution at R3 which has a halogen or alkoxy group (74f–74i) triggered a slight rise in cellular potency While using the halide analogs (74g–h) demonstrating optimum the potency while in the group. Further optimization triggered the discovery of 74i–j, with 74k as essentially the most active compound from the series https://indazoleproducts43196.blog5star.com/31879568/indazole-fungicide-an-overview